TMPS oral Paste 1 kg

The combination of sulfadiazine + trimethoprim (TMPS) act synergistically to kill a wide range of susceptible bacteria and reduces the possibility of bacterial resistance developing.

The combination blocks the synthesis of bacterial folates at two critical points, which are essential for bacterial cell multiplication and survival. The combination of sulfadiazine + trimethoprim is bactericidal, while either drug alone is bacteriostatic. Folate synthesizing bacteria which are resistant or moderately resistant to either drug alone are frequently susceptible to the combination.